When Jessica Lowe steps into a room, people tend to take notice. Sometimes it’s the pink scrubs, sometimes it’s the heels, and often it’s the unmistakable confidence that follows her wherever she goes. But what people quickly learn is that beyond the style is a double-boarded neurologist and epileptologist whose knowledge has earned her recognition in her field. Known to the world as Doctor Brain Barbie, Jessica has built a career on showing that intelligence and individuality can coexist. Instead of being in opposition, they can work together to make a significant impact and challenge perspectives.
Her path to medicine began in The Bahamas, where she grew up before moving to the United States to pursue medical studies. She earned her degree in neurobiology with magna cum laude honors, went on to graduate summa cum laude from Ross University School of Medicine on a full scholarship, and completed her residency and fellowship training in neurology and epilepsy in Michigan. Along the way, she rose to Chief Resident and gained a reputation for both clinical excellence and leadership. She later became the first physician in her region of Delaware to serve as both a neurohospitalist and epileptologist, helping to build programs that expanded access to critical neurological care.
But what sets Jessica apart is not only her clinical skill. It’s her decision to bring her personality into the room. Too often, medicine teaches women to mute themselves, to conform to an image that diminishes their creativity and individuality. Jessica decided early on that she would not do that. She would show up as herself—lipstick, heels, humor, and all—and still provide high-quality, evidence-based care. For her, authenticity has become a strength that contributes to her effectiveness as a doctor.
Her brand, Doctor Brain Barbie, emerged from that conviction. Initially, it was a way to answer questions and share knowledge online, but it has evolved into something much larger. Today, it serves as a platform that connects scientific knowledge with everyday language, bringing neurology to audiences that traditional medical education often overlooks. Jessica creates content that is both approachable and relatable, covering everything from seizures and epilepsy to migraines and stroke awareness. One of her most impactful moments came when a follower messaged her to say that, because of her videos, she recognized her symptoms as seizures, sought help, and was eventually diagnosed correctly. Those moments remind her that beyond clicks or shares, her work can make a meaningful difference in people’s lives.
The cultural side of Doctor Brain Barbie is just as important. Jessica’s viral “McMigraine” trend helped raise awareness of a heavy topic, proving that even complex conditions can be explained in ways that resonate with a large audience. Her ability to merge humor, education, and advocacy has made her not just a doctor with a social media presence but a trusted voice that people listen to. She knows how to speak “doctor” and “human” at the same time, making her one of the rare figures who can engage both patients, professionals, and the public in meaningful ways.
Jessica has faced challenges along the way. Gender bias in medicine remains an issue. She has been mistaken for a nurse after introducing herself as a doctor. She has had to prove herself repeatedly in male-dominated spaces, where style was misinterpreted as softness and femininity as a lack of seriousness. But each time she was underestimated, she responded not by shrinking, but by standing taller. When she once walked into a stroke code in stilettos, the silence in the room was only broken when she called the next step in the algorithm. Her voice was heard over any assumptions made about her.
Her advocacy extends beyond hospitals and online platforms. She serves on the board of the Epilepsy Foundation of Delaware and is an executive leader for the American Heart Association’s Go Red for Women campaign. In 2025, she was named the American Heart Association Woman of Impact, leading a team that raised over $88,000 for heart health initiatives. For Jessica, that campaign was deeply personal. She dedicated her efforts to a young heart survivor named Noelle Hunter, whose courage and optimism served as an inspiration to her throughout the process. Every dollar raised felt like a step toward supporting women like Noelle, whose stories and futures matter.
Looking ahead, Jessica envisions Doctor Brain Barbie continuing to grow into a global movement. She dreams of hosting a health-focused television show, developing new tools for patient education, and creating a network of women in medicine who can confidently stand in both their brilliance and their individuality. She hopes to inspire young women to know that they can walk into a room and be themselves—whether in pink scrubs or a power suit—and still earn respect. She wants to show that expertise can come in many different forms, faces, and styles.
Jessica’s story is not just about medicine. It’s about representation, resilience, and redefining leadership. She is proving that the face of healthcare can be intelligent, stylish, and strong all at once. She is demonstrating that knowledge does not need to be delivered in sterile language to be taken seriously. And she is reminding patients and professionals alike that authenticity can be one of the most influential forms of authority.
Doctor Brain Barbie is not a gimmick. It’s Jessica’s way of challenging how people perceive medicine and how medicine perceives women. Her mission is to make brain health accessible, advocate for those who feel unheard, and leave the door open for the next generation of women who are ready to lead.
Follow her journey on Instagram and TikTok at @doctorbrainbarbie to see how she is transforming science into something human, relatable, and unforgettable.